Zúñiga-Pflücker Lab
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Immunohistologic analysis of thymus sections.
Green: anti-CK8 (cortical)
Blue: anti-CK5 (medullary)
Red: anti-hCD45 (thymocyte)
2002 – Our lab established OP9-DL1 cell line, the gold standard for using generating T cells from mouse blood stem cells outside of the thymus. Over a 1,000 labs investigating T cell development and functions around the world have requested this cells line.
2003 – Our lab was able to show differentiation of mouse embryonic stem cells to T cells using the OP9-DL1.
2005 – We showed human blood stem cells derived from cord blood differentiated into T cells in culture.
Adult mouse thymus.
Green: anti-CK8 (cortical)
Blue: anti-CK5 (medullary)
Red: anti-hCD45 (thymocyte)